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Research Article

ECB. 2019; 8(9): 318-321


ONE-POT SYNTHESES OF 2-(1H-BENZO[d]OXAZOLE-2-YL)-NARYLBENZAMIDES BY SELF-CATALYSIS

V. Ramesh, G. Purna Chander Rao, D. Ramachandran, A. Kalyan Chakravarthy.




Abstract

A novel, efficient, and high-yielding one-pot three-component method was developed for the synthesis of 2-(1H-benzo[d]oxazole-2-yl)-Narylbenzamides by combining phthaldichloride with anilines & o-aminophenol in water without any external catalyst. The environmentally friendly procedure, easy operation and mild reaction conditions enable the tolerance of a wide scope of functionalities as well as high reaction efficiency.

Key words: Water, phthaldichloride, anilines, o-aminophenol, 2-(1H-benzo[d]oxazole-2-yl)-N-arylbenzamides






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