It has been found that 4-nitrophenylglyoxal reacts with N-alkoxy-N’-arylureas and N-alkoxy-N’-alkylureas in acetic acid medium with the selective formation of the diastereomers of the 3-alkoxy-1,5-diaryl-4,5-dihydroxyimidazolidin-2-ones and 3-alkoxy-1-alkyl-5-aryl-4,5- dihydroxyimidazolidin-2-ones with cis-orientation of OH-groups. The X-ray structural analysis of 3-propyloxy-4S,5S-4,5-dihydroxy-1- methyl-5-(4-nitrophenyl)imidazolidin-2-one and of 3-n-butyloxy-4S,5S-4,5-dihydroxy-1-(4-methylphenyl)-5-(4-nitrophenyl)imidazolidin- 2-one has demonstrated this structural feature of these compounds.
Key words: 4-Nitrophenylglyoxal, N-alkoxy-N’-arylureas, N-alkoxy-N’-alkylureas, 3-alkoxy-1,5-diaryl-4,5-dihydroxyimidazolidin-2- ones, 3-alkoxy-1-alkyl-5-aryl-4,5-dihydroxyimidazolidin-2-ones, synthesis, structure.
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