Synthesis of 3,4-dihydropyrimidin-2(1H)-one and 3,4-dihydropyrimidin-2(1H)-thione derivatives from aldehydes, ethyl acetoacetate and urea or thiourea using glycerol as an organo OH-acid, green and reusable catalyst is reported. The practical and simple protocol led to excellent yields of the dihydropyrimidin-2(1H)-one and thiones under mild reaction conditions and within short span of reaction times with easy reaction workup by maintaining excellent atom economy
Key words: Organic OH-acid, reusable catalyst, glycerol, dihydropyrimidin-2(1H)thione, dihydropyrimidin-2(1H)one.
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