QUALITY OF LIFE OF PATIENTS RECEIVING A SINGLE OR COMBINATION OF CALCIUM CHANNEL BLOCKER-ANGIOTENSIN RECEPTOR BLOCKER: A CROSS-SECTIONAL STUDY IN WEST JAVA, INDONESIA
The prevalence of hypertension, based on Indonesian Basic Health Research 2018, was 34.1%. Hypertensive patients usually show a low quality of life (QoL) due to their lifelong drug dependence. This cross-sectional study was conducted to determine the QoL of adult hypertensive patients treated with a single calcium channel blocker (CCB) and combination of CCB and angiotensin receptor blocker (ARB) at a primary referral hospital in West Java during December 2018 to February 2019. The QoL of the patients was determined using the Indonesian validated-EQ5D5L and EQVAS questionnaires. 83 adult hypertensive outpatients were recruited and agreed to participate in this study. Of the 83 hypertensive patients, 44.6% were being treated with a single CCB and 55.4% were being given the combination of CCB and ARB. The characteristics of the patients were age 51 ± 1.04 years, 71.3% female, 84.3% married, 66.2% never undertook physical activity, daily drugs consumed 4 ± 0.19 items and the duration of hypertensive therapy was 20 ± 3.3 months. Most of the patients indicated problems in the area of pain and anxiety. Hypertensive patients treated with a combination of nifedipine and candesartan indicated the best QoL, whereas the lowest QoL was found in patients treated with a combination of nifedipine and valsartan.
Key words: angiotensin receptor blocker, calcium channel blocker, hypertension, quality of life
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