ONE POT, FOUR-COMPONENT SYNTHESIS 2-AMINO-6-(1,4- DIOXO-3,4-DIHYDROPHTHALAZIN-2(1H)-YL)-4-ARYL-4HPYRAN-3,5-DICARBONITRILES IN AN IONIC LIQUID

ECB. 2019; 8(3): 105-109

D. P. Loka Maheshwari, B. Satyanarayana.

Abstract
[DBUH][OAc] (1,8-diazabicyclo[5.4.0]-undec-7-en-8-ium acetate) mediated, green synthesis of 2-amino-6-(1,4-dioxo-3,4- dihydrophthalazin-2(1H)-yl)-4-aryl-4H-pyran-3,5-dicarbonitriles have been synthesized by condensing diethyl phthalate, ethyl cyanohydrazide, benzaldehydes and malononitrile in [DBUH][OAc] medium, at 60-65 oC for 2 h. Particularly valuable features of this method include high yield, broad substrate scope, shorter reaction times and straightforward procedure Key words: Diethyl phthalate, benzaldehydes, ethyl cyanohydrazide active methylene compounds; 1,8-diazabicyclo[5.4.0]-undec-7- en-8-ium acetate