Au-MOPS(3-MORPHOLINOPROPANE-1-SULFONIC ACID) COUPLED CATALYST FOR THE SYNTHESIS OF 3-AMINOALKYLATED INDOLES
Suryakant B. Sapkal, Sadanand Y. Guhe, Sanjay N. Harke, Balaji R. Madje, Suchita S. Gadekar.
Abstract
Gold nanoparticles (Au NPs) coupled with 3-morpholinopropane-1-sulfonic acid (MOPS) for catalytic performance to the cyclocondensation reaction of aromatic/heteroaromatic/aliphatic aldehydes, indole and aromatic/heteroaromatic amines have been demonstrated for the first time in favour of 3-aminoalkylated indoles in ethyl alcohol at reflux temperature. Reaction conditions are just like ambient nevertheless all chemical transformations completed smoothly contributing worthwhile for the synthesis of 3-aminoalkylated indoles.
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