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Research Article

ECB. 2018; 7(12): 345-347


NICKEL ACETYLACETONATE CATALYZED KNOEVENAGEL CONDENSATIONS AT ROOM TEMPERATURE

Manojkumar U. Chopade,Anil U. Chopade, Santosh V. Padghan.




Abstract

Nickel acetylacetonate (Ni(acac)2) as a catalyst was tested in Knoevenagel condensation of benzaldehyde with ethyl cyanoacetate in DMSO to provide α-cyano ethyl cinnamate. The substituted benzaldehydes and 3-methylbutyraldehyde gave similar reaction and the corresponding products were obtained in good yields (78-92%) under clean and straightforward condition.

Key words: Knoevenagel condensation, Ni(acetylacetonate)2; benzaldehydes; ethyl cyanoacetate.






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