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Original Research

Med Arch. 2013; 67(5): 342-345


Improved Glycaemic Control with Insulin Glargine as Part of a Basal-bolus Regimen in T2DM Patients Inadequately Controlled on Premixed Therapy

Belma Ascic Buturovic, Alen Lekic, Natasa Grulovic.




Abstract

Objectives: Monitoring efficacy of insulin glargine administered to patients with diabetes mellitus type 2 (DMT2) in combination with rapid-action insulin and analogues, where the hitherto fixed-mixture insulin therapy failed to achieve a satisfactory glycaemic control (HbA1c < 7%) following a six-month fixed-mixture insulin therapy. Design: Open, observational, multicentric, non comparative, prospective product registry. Results: 9-month prospective observational study recruited DMT2 patients previously uncontrolled on premixed insulin (HbA1c > 7%). Total of 278 subjects were documented in the study. At 9 months of follow-up 45,3% of patients reached a target HbA1c level

Key words: Type 2 diabetes mellitus, insulin glargine, HbA1c, premixed insulin.






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