Abstract

Background: There are different publications on the relationship between the infections and development of allergic diseases.

Aims & Objective: To examine the relationship between Helicobacter pylori infection and allergic rhinitis during childhood.

Materials and Methods: 50 dyspeptic patients, 30 patients suffering from allergic rhinitis (overall 48 paediatric and 32 adolescent age groups) additional to 20 children from paediatrics polyclinics as control were included in this study. The serums of all of the patients were studied with respect to existence of specific IgE developed from house dust mites, cat's fur, rye grass and pine tree, using IgG.

Results: 33.3% (16/48) of the cases from paediatric group and 31.3% (10/32) of the cases from adolescent group were diagnosed with H pylori IgG positive.10.4% (5/48) of the cases from paediatric group and 31.3% (10/32) of the cases from adolescent group were diagnosed with allergic rhinitis. Contrary to the paediatric group, the number of the cases diagnosed with allergic rhinitis IgG was significantly more while the number of the cases diagnosed with H pylori IgG positive was less in the adolescent group (p=0.84and p=0.019). Furthermore, the level of specific IgE developed from rye grass (18.8% vs 4.2%) was determined to be significantly higher in the adolescent group than the paediatric group (p=0.033).

Conclusion: Contrary to the paediatric group, the number of cases diagnosed with allergic rhinitis is higher while the number of cases diagnosed with H pylori infection is less in adolescents.

Key words: Helicobacter Pylori; Allergic Rhinitis; Children