Abstract The low percentage of high-density lipoprotein-cholesterol (HDL-C) is strongly accompanied with cardiovascular diseases (CVD) where female are at higher risk than male and are the most dangerous reason of a disease called type 2 diabetes mellitus (T2DM). Although the relationship between gender-specific HDL-C / LDL-C level and T2DM is difficult to understand, however, it is suspected to be linked. To determine the HDL-C and LDL-C ratios among males and females with T2DM subjects, a study was conducted in the Department of Biochemistry Laboratory of BUHS general hospital, Mirpur, Dhaka, Bangladesh from July 2018 to November 2018 among 60 T2DM patients consisting of 30 males and 30 females. Study subjects with ages ranging from 35-65 were included in this study. Serum glucose and lipid profile was analyzed by enzymatic colorimetric method. Among the glycemic profile, the fasting serum glucose levels and 2 h after breakfast (ABF) glucose levels in male and female subjects were measured. The total serum cholesterol was significantly higher in the subject of females T2DM patient compared to male T2DM subjects (p=0.043). However, HDL-C and LDL-C does not show any significant difference between male and female T2DM subjects. In conclusion, our results show hypercholesterolemia among female T2DM subjects compared to male counterparts who might have higher risk of cardiovascular diseases.
Key words: Triglyceride, HDL-C, LDL-C, Type 2 diabetes mellitus, Cardiovascular
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