Abstract

Introduction: The Pandemic of SARS COV-2 continues to be a global health threat which has affected 140 million cases all over the world with 3.01million deaths with the main underlying main cause of raised inflammatory markers. India is well known for the birth of Ayurveda – the potential therapeutic agents have been developed having combination of already proven drugs for research.
Objectives: To measure the effect of drug- “Immune” on the neutralizing antibody levels along with inflammatory markers among mild to moderate symptomatic COVID-19 subjects.
Material and methods: Triple blinded Randomized Controlled Trial was adopted in our study among mild and moderate cases of COVID-19. Two groups- each having 25 subjects were intervened along with standard care of treatment where one was getting the drug immune consisting of Withania somnifera , glycrrhizine gabra , Cederus Deodara and Leptadenia Reticulata in Arka preparation and other were getting placebo which was blinded by labelling as drug A and Drug B. These two groups were followed up for antibody testing and inflammatory markers such as interleukin-6,D-dimer,serum ferritin and lactate dehydrogenase were also assessed.
Results: There was a statistical significant rise in antibody titres(P value

Key words: COVID-19, Immunological effect, Ayurveda formulation