ABSTRACT
Objective
To ascertain the features and characteristics of colorectal cancer in North Jordan in patients at Prince Rashid Military Teaching Hospital during 2005-2007.
Patients and Methods
Patients with large bowel cancer were reviewed. Data collected included age, gender, site of tumor, presentation, histology, extension of tumor and nodal involvement and treatment.
Results
There were 69 new cases of colorectal cancer (42 males and 27 females) admitted to the hospital during the period 2005-2007. Cancer was diagnosed preoperatively by colonoscopy in 64% of the cases. Median age of patients was 61.2 for males and 62.3 for females in 2005, 63.8 males and 56.4 for females in 2006 and 59.1 males and 55.4 for females in 2007. The most common tumor grade was moderately differentiated (69%), then poorly differentiated (17%) and then well differentiated (14%). Mean annual incidence was 23 patients/year. Nine (13 %) patients were equal or under the age of 50 years, the presenting symptoms. Descend0ing and sigmoid colon were the most common anatomical sites affected (60 out of 69 patients). The most common histopathological type was adenocarcinoma.
Conclusion
The findings of age affected were equal or less than 13% (i.e. equal or less than 50 years) indicates the need for cancer screening and prevention in Jordan. The best method to diminish the incidence of colorectal cancer today may be to increase the use of screening colonoscopy and biopsy. The changes in incidence strongly suggest that proximal and distal colonic cancers are different diseases or have a different pathogenesis or etiologies. (Rawal Med J 2010;35: ).
Key words
Colon carcinoma, polyps, colorectal cancer.
INTRODUCTION
Incidence of colorectal cancer (CA Colon) has been increasing during the last years and 5% of the population gets affected.1 It is a preventable disease as CA colon usually develops slowly from an identifiable precursor lesion, the adenoma.2 One in 17 women will develop CA colon.3 Risk factors include age, a diet rich in fat and cholesterol, inflammatory bowel disease (especially ulcerative colitis), and genetic predisposition, including hereditary polyposis and nonpolyposis syndromes. If detected early, colorectal cancer is curable by surgery. The objective of this study was to identify better the features and characteristics of CA colon in North Jordan among patients at Prince Rashid Military-Teaching Hospital in 2005-2007 period.
PATIENTS AND METHODS
The data of all patients with large bowel cancer in Prince Rashid Military-Teaching Hospital were obtained. Variables recorded included age, gender, site of tumor, presentation, histology, extension of tumor and nodal involvement, and treatment.
RESULTS
There were 69 new cases of CA colon (42 males and 27 females) admitted to the hospital during the period 2005-2007. Cancer was diagnosed preoperatively by colonoscopy in 64% of the cases. Median age incidence for colorectal carcinoma was 61.2 for ma
Key words: Colon carcinoma, polyps, colorectal cancer.
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