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Serum lipid profile in Helicobacter pylori infected patients

Saad Al-Fawaeir, Mohammad Abu Zaid, Ayman Abu Awad, Baker Alabedallat.




Abstract

Background: Helicobacter pylori (H. pylori) is a controversial risk factor for atherosclerosis. An association between H. pylori infection and lipid concentrations has been reported.
Aim: the aim of this study was to investigate any possible association between H. pylori infection and serum lipid levels.
Design and methods: the study population consisted of 350 subjects. H. pylori infection status was determined by assaying serum anti-H. Pylori immunoglobin G antibody (IgG). Triglyceride, total cholesterol and HDL-cholesterol were measured for each subject; the data were compared among H. pylori infected subjects and healthy group.
Results: A total of 77% of the subjects were positive for H. pylori IgG antibodies and 23% were antibody-negative. The serum cholesterol concentrations were significantly higher in patients group when compared with healthy group (189.32±45.15 vs. 179.41±36.37 mg/dL (p

Key words: Helicobacter pylori; lipid profile; atherosclerosis; immunoglobin G antibody.






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