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Synthesis, characterize and antioxidating activity of the inclusion complex of Wogonin with β-cyclodextrin and hydroxypropyl-cyclodextrin

Jinxia Li, Jianping Bai, Kenming Yu, Huizhi Zhang, Jianbin Chao.




Abstract

The aim of the study was to synthesize the complexes of Wogonin with β-CD and HP-β-CD by refluxing method, and the experimental resulted confirmed the forming of Wogonin complexes with CDs by nuclear magnetic resonance spectroscopy, infrared spectra and differential scanning calorimetry at 60 ℃ refluxing for 6h. Kinetic studies of DPPH• with Wogonin and CDs complexes were done. The results obtained indicated that the Wogonin/HP-β-CD complex was the most reactive form.

Key words: Wogonin; Cyclodextrins; NMR; IR; DPPH•






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