Dengue fever is important cause of acute febrile illness in post–monsoon season in India. This study was done to record the incidence of Dengue in admitted patients with acute febrile illness in hospital setting. Study also intends to record the clinical, biochemical, outcome profile of paediatric dengue cases admitted in tertiary centre in Eastern Uttar Pradesh, India. It was prospective case record analysis at tertiary care research hospital in Eastern Uttar Pradesh. The study recruited fifty three children (< 18 years) with serology proven diagnosis of Dengue disease. Disease was confirmed by doing Ns1Ag, IgM antibody test by ELISA method. Six hundred children were screened and 53 met the inclusion criteria. Incidence of Dengue disease in hospitalised acute febrile illness was 8.8 percent. There were thirty one males. Mean age of presentation of study population was 9.32±5 years with range 0.25-17 years. Fever (94%), nausea and vomiting (59 %), abdominal pain (55%), persistent vomiting (49%), thrombocytopenia (< 100,000 [66%]), petechiae and purpura (43%) were the important clinical manifestations. Six required intensive care monitoring. There was only one death. Dengue fever is important cause of acute febrile illness in children. Case fatality rate can be minimised with proper World Health Organization (WHO) classification and protocol based management of cases.
Key words: Dengue fever, paediatric, outcome, Eastern Uttar Pradesh.
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