Aim: The aim of this study was to present cases of Lance Adams Syndrome (LAS) and the results of treatment following cardiopulmonary resuscitation (CPR).
Methods: This study included patients in the intensive care clinic between May 2012 and January 2017 in hospital after CPR in the intensive care unit. A retrospective review was made of the files of patients who were evaluated by the Neurology Department because of epileptic seizure.
Results: Evaluation was made of 19 patients with no history of epilepsy/antiepileptic drug use and treatment initiated by the Neurology Clinic for LAS. The patients comprised 11 males (58%) and 8 females (42%) with a mean age of 55.89 ± 19.65 years for survivors and 61.50 ± 16.12 years for non-survivors. The mean length of hospital stay was 35 days for survivors and 17.5 days for non-survivors.
Outcomes were determined as mortality in 10 cases, long-term care in 7, and discharge with recovery in 2. Sodium valproate was used in 4 patients and levetiracetam in 15. The 7 patients on long-term care were found to have been lost in the 3-month period after discharge.
Conclusions: In this syndrome, the EEG may not provide any pathological data or show epileptic changes. The pathophysiological mechanisms of LAS are unknown and definitive treatment options are limited. However, an early start to treatment can lead to better prognosis. It can be concluded that after CPR, myoclonic contractions can be reduced, and morbidity and mortality can improve with early diagnosis and early treatment.
Key words: Post-hypoxic myoclonus; Post resuscitation; Lance Adams syndrome
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