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Adverse drug reactions associated with drugs inducing osteoporosis

Mohammed Taqui, Swamivelmanickam M, Mohathasim Billah A.




Abstract

Drug-induced osteoporosis has a widespread and has a profound impact on the prognosis of patients in chronically serious patients. The most common medicines that cause osteoporotic fractures have been glucocorticoids but in women therapy with aromatase inhibitors, fractural osteoporosis is also identified, Type 2 diabetes mellitus treatment for men and women who are treated with antiandrogen therapy in prostate cancer and women treated with elevated amounts of thyroxine following menopausal procedures. Fracture bone loss also occurs with people who are treated with immune systems drugs such as calcineurin inhibitors, proton-pump inhibitors, heparin, antiretrovirals, loop diuretics, serotonin reuptake selective inhibitors, oral anticoagulants, and anticonvulsants.

Key words: Drugs; Fractures; Osteoporosis; Secondary Osteoporosis






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