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Platelet Count and Eosinophilia in Peripheral Blood and Rheumatoid Arthritis

Mohammad Mahdi Eftekharian, Alireza Zamani.




Abstract

Aim: Rheumatoid arthritis is a chronic autoimmune inflammatory disorder of flexible joints with unknown etiology, which afflicts 1% of the world's population. The aim of this study was to investigate the association between platelet count and eosinophilia in peripheral blood and history of blood transfusion with RA in Hamadan city, west of Iran. Methods: As a case-control study, data of Complete Blood Count tests and filled questionnaire with written consents from 128 patients and 129 age and sex matched controls, were collected and analyzed by Pearson Chi-Square test using SPSS. Results: In the case and the control groups, there were 116 and 117 females, respectively. Statistical analysis showed that there was no significant association between platelet count and eosinophilia in peripheral blood and history of blood transfusion with the RA (p > .05). Conclusion: Considering previous global investigations on this topic with controversial results and the result of our study, it seems more studies are needed to determine the definitive association between platelet count and eosinophilia in peripheral blood and history of blood transfusion with RA.

Key words: Rheumatoid arthritis, Platelet, Eosinophilia, Blood transfusion, Blood parameters, Risk factors






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