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RMJ. 2026; 51(3): 692-695 Efficacy of triamcinolone acetonide injections in the management of oral submucous fibrosis at a tertiary care hospital, Karachi, PakistanHoney Rajpal, Jehan Alam, Maryam Mughal, Waiza Batool, Grinthi Rajpal, Mor Khan Shar. Abstract |  Download PDF | |  Post | Objective: To evaluate the efficacy of intralesional triamcinolone acetonide injections in the management of oral submucous fibrosis (OSF) at a tertiary care hospital in Karachi.
Methodology: This quasi-experimental study was conducted in the Department of Oral and Maxillofacial Surgery, JPMC, Karachi, from March to September 2025. Eighty-eight clinically diagnosed OSF patients were recruited by convenience sampling. Each received weekly submucosal 1.5ml dose of triamcinolone acetonide with lignocaine for four consecutive weeks. Mouth opening, burning sensation, mucosal stiffness, and blanching were recorded after each dose. Data were analyzed using SPSS 20. For assessment of association among the clinical outcomes, a chi-square test was used, and p
Key words: Burning sensation, fibrosis, intralesional injections, oral submucous fibrosis, triamcinolone acetonide.
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