Microorganisms in present time are found increasingly resistant to antibiotics. This trend is obviously posing serious threat to health care delivery. The antibacterial efficacy of aqueous and alcoholic extracts of Psidium guajava were investigated against clinically isolated Staphylococcus aureus, Staphylococcus saprophyticus and Salmonella species using agar diffusion method. The extracts were found to exhibit antibacterial activities. Zones of inhibition obtained ranged between 1.0 mm and 15.0 mm with S.aureus being the most susceptible while S. saprophyticus poised the highest resistance. Minimum inhibitory concentrations obtained were between 5.0 and 6.0 mg/ml while minimum bactericidal concentration, MBC ranged from 4.0 to 6.0mg/ml. The plant exhibited antimicrobial activity, therefore exploring its medicinal potentials for therapeutic purpose is essentially necessary.
Key words: Antimicrobial Activity, Inhibitory Concentration, Bactericidal, Leaf Extract and Psidiun guajava.
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