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Effect of cigarette smoking on erythrocyte sedimentation rate and total leukocyte count

Rashmi N Gitte, Raju Taklikar.




Abstract

Background: Cigarette smoking is one of the major lifestyle factors which influence the health of human beings. Erythrocyte sedimentation rate (ESR) is a certain biomarker of inflammation. It was a significant predictor of heart failure.

Aims and Objectives: This study was conducted to find the effect of cigarette smoking on ESR and total leukocyte count (TLC).

Materials and Methods: A total of 120 healthy male smokers and 120 healthy male non-smokers among hospital employees and people from surrounding areas of Navodaya Medical College, Raichur (India), were studied. The TLC was done using Beckman Coulter Automatic Analyzer; ESR estimation was done by Westergren’s method.

Results: The mean ESR for smokers is 11.74 mm/h and for non-smokers 7.38 mm/h. The mean TLC for smokers is 8050 per mm3 and for non-smokers 6858 per mm3. The difference between mean ESR and TLC of smokers and non-smokers was statistically significant (P < 0.0001).

Conclusion: We concluded that, in smokers, ESR and TLC increased significantly. Regular monitoring of these two parameters in smokers is advised.

Key words: Cigarette Smoking; Erythrocyte Sedimentation Rate; Total Leukocyte Count






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