Background: Smoking can induce cancer, stroke, and heart disease and also has been reported to cause periodontal disease, gastric ulcer, sudden infant death syndrome, and metabolic syndrome.
Objectives: The objective is to study and compare alterations of lipid profile among smokers and non-smokers in different age groups.
Materials and Methods: One hundred participants were studied at JA Group of Hospitals and GR Medical College, Gwalior, from June 2014 to October 2015 after dividing them into Group A (n = 50, non-smokers) and Group B (n = 50, smokers). Lipid profile including total cholesterol (TC), triglycerides (TGs), low-density lipoproteins (LDLs), high-density lipoproteins (HDLs), and HDL/TC ratio was estimated.
Results: The mean age of participants in Group A and Group B was 34.56 ± 12.12 and 36.45 ± 62.22 years, respectively. TC, TG, and LDL were higher in Group B compared to Group A, whereas HDL and HDL/TC ratio were lower in Group B compared to Group A across all age groups.
Conclusion: Significantly higher serum level of TC, TG, LDL, and very LDL with lower level of HDL suggests that smoking is associated with dyslipidemia. Dyslipidemia is an independent risk factor for vascular diseases, so it can be used as a biomarker to identify smokers at risk.
Key words: High-density Lipoprotein; Low-density Lipoprotein; Smoking; Total Cholesterol; Triglycerides
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