Background: Refractive surgery can induce or exacerbate symptoms of dry eye. Dry eye syndrome causes discomfort, fluctuations in visual quality, slower healing, epithelial damage, and can lead to regression of refractive errors and reduced visual quality. In most patients, symptoms are mild, do not cause disturbances, and pass within 6 months when the period of healing ends. Objective: To compare tear film after Laser in Situ Keratomileusis (LASIK) using two methods of flap creation. Methods: Retrospective analysis of tear film characteristics after flap creation with two mechanical microkeratomes (group I Moria M2, group II Moria SBK One Use Plus) and one femtosecond laser (group III Ziemer Femto LDV) was conducted. One hundred and fifty-four respondents (50 in each group) were enrolled in the study, with myopia from -0,50 D to -7,50 D and up to 2,50 D of astigmatism with best-corrected visual acuity of 0,00 Log MAR. Schirmer test and Tear Break Up Time (TBUT) test were measured after 1 week, 1, 3, 6, and 12 months after the surgery. Results: In all three groups values of the Schirmer test significantly decreased after the surgery (p
Key words: LASIK, mechanical microkeratome, femtosecond laser, TBUT, Schirmer test.
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