Abstract

Objective: This study aimed to examine the interactions between lifestyle, sociodemographic, psychiatric, and body-image variables in Saudi adults on antidepressants and body mass index (BMI).
Methods: This cross-sectional study was conducted in psychiatric clinics in the Eastern Province of Saudi Arabia. Demographic and lifestyle data, depression and anxiety levels, and body shape satisfaction were assessed using a structured questionnaire and validated Arabic versions of the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Body Shape Questionnaire-8.
Results: This analysis included 206 participants, predominantly 0.05).
Conclusion: It was found that inactivity, older age, and higher income were correlated with higher BMIs in Saudi patients taking antidepressants, particularly selective serotonin reuptake inhibitors. Body-image dissatisfaction mediated an association between psychological distress and weight. This demonstrated the need for culturally tailored psychiatric interventions in Saudi Arabia that incorporate behavioral activation, nutrition counseling, and proactive weight monitoring.

Key words: Antidepressants, BMI, depressive disorders, exercise, Saudi Arabia.