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Relationship between prostate cancer and atypical small acinar proliferation

Onur Ceylan, Rabia Demirtas, Ali Kurt, Yusuf Can, Mehmet Esref Kabalar, Ahmet Erkan Bilici, Hilal Balta, Ilknur Calik, Sevilay Ozmen, Senay Erdogan Durmus.




Abstract
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Aim: To investigate the prostatic adenocarcinoma (PA) detection rate in follow up biopsies with an initial diagnosis of atypical small acinar proliferation (ASAP).
Materials and Methods: In this study, the cases of ASAP diagnosis in prostate needle biopsy materials between January 2010 and December 2016 were retrospectively analyzed and the correlation between the results and the follow-up diagnoses of ASAP-diagnosed cases was investigated.
Results: 62 cases with ASAP were included in the study and 21 (34%) of them were detected as PA after the follow-up diagnoses. Also ASAP and PA were detected at different localizations in 38% of the cases.
Conclusion: We are on the opinion that it is important to increase the number of samples taken from other localizations as well as ASAP diagnosed quadrants when taking follow-up biopsies.

Key words: Atypical Small Acinar Proliferation; Prostate Cancer; Prostate Needle Biopsy






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