Background: Hypothyroidism refers to a state that results in a deficiency of thyroid hormones, including hypothalamic or pituitary disease and generalized tissue resistant to thyroid hormone. Thyroid-releasing hormone can cause a rise in serum prolactin levels in patients of primary hypothyroidism.
Objective: The objective of the study was to find the levels of serum prolactin in patients who are having hypothyroidism and to observe the relationship of prolactin with thyroid-stimulating hormone.
Materials and Methods: A total of 150 patients coming to endocrinology clinic for thyroid-related problems were selected for the study and analyzed for their serum T3, T4, thyroid-stimulating hormone (TSH), and prolactin levels by enzyme-linked fluorescent assay technique using Vidas autoanalyzer from Biomeriuex, France.
Results: Prolactin level is high in the subclinical hypothyroid patients and hypothyroid patients as compared to euthyroid patients.
Conclusion: In our study, it was seen that the levels of prolactin rise in relation to rising TSH level in hypothyroid patients.
Key words: Prolactin, Hypothyroidism, T3, T4, Thyroid-stimulating Hormone
|
