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Myocardial dysmorphism and functional failure: A cardiac sting in patients with advancing chronic obstructive pulmonary disease

JUGAL KISHORE BAJPAI,SUDHIR MODALA,SUNIL KUMAR,DEEEPKA KUMAR DAS.




Abstract
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Background: Extrapulmonary cardiac manifestations in chronic obstructive pulmonary disease (COPD) exhibit a great deal of deterioration in ventricular geometry and function, contributing to high mortality and morbidity. Echocardiography data regarding ventricular remodeling and functional deterioration in COPD patients are rare and insufficient.

Aims and Objectives: The aim of the study was to assess and compare the early deterioration of ventricular geometry and function by echocardiography in COPD (Group-2) and non COPD patients (Group-1).

Materials and Methods: In this study, 150 individual patient data (IPD) patients diagnosed of COPD admitted in a pulmonary unit of Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, between 30 and 80 years of both the sexes, were analyzed randomly (Group-2). Retrospective comparative study was undertaken with the same number of IPD patients admitted for other ailments (Group-1). Pulmonary function test, electrocardiography, and two-dimensional-echocardiography were done to assess and compare the ventricular geometry and function.

Results: The study revealed a significant increase in the echo parameters such as left ventricular (LV) internal dimension in diastole (

Key words: Chronic Obstructive Pulmonary Disease; Two-Dimensional-echocardiography; Left Ventricular Hypertrophy; Diastolic Dysfunction






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