Home|Journals|Articles by Year|Audio Abstracts
 

Case Report

IJMDC. 2020; 4(12): 2378-2380


Late onset of glucose-6- phosphate dehydrogenase deficiency with methemoglobinemia: a case report

Jaffar Saleh Alsayigh, Abdullah Mohammed Almuebid, Ahmed Dkhail Bohliqah, Dunya Alfaraj.




Abstract

Background: Glucose-6- phosphate dehydrogenase (G6PD) is an enzyme that plays a vital role in eliminating reactive oxygen species (ROS) which are considered to be toxic to the cells. Deficiency of this enzyme causes hemolysis. This study presents a case of a middle-aged woman with the late onset of G6PD with methemoglobinemia.
Case Presentation: A case of 57-year-old female was reported, who was presented to the emergency department with jaundice, dyspnea, dark urine and low oxygen saturation. On further investigation the patient's methemoglobin level reached up to 5.1%. Thus, the patient was diagnosed with the late onset of G6PD with methemoglobinemia.
Conclusion: The G6PD deficiency could present late in life especially in areas with mild variants. On rare occasions, it could be present with severe hemolysis associated with methemoglobinemia. In these cases, it is important to find the cause. The use of methylene blue as an antidote is harmful.

Key words: G6PD, methemoglobinemia, favism, deficiency, case report






Full-text options


Share this Article


Online Article Submission
• ejmanager.com




ejPort - eJManager.com
Refer & Earn
JournalList
About BiblioMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Bibliomed are open access articles licensed under Creative Commons Attribution 4.0 International License (CC BY), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.