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Original Article



The utility of ischemia modified albumin as an oxidative stress biomarker in seborrheic dermatitis

Gülhan Aksoy Saraç,Aynure Öztekin,Ünsal Savcı,Engin Şenel,Coşkun Öztekin,Saadet Kader,Turan Akdağ,Salim Neşelioğlu,Özcan Erel.




Abstract
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Background: Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease that occurs as scaly reddish-brown itchy patches on sebaceous, gland-rich areas of the scalp, face, and trunk. The relation between SD disease and serum IMA(Ischemia modified albumin) levels remains unknown.
Aim: To investigate the potential role of serum IMA and corrected IMA levels in SD disease.
Materials and methods: Thirty-seven participants who were diagnosed with SD disease and sixty-two healthy subjects (control group) were enrolled in the study. Venous blood samples were collected from each participant, and serum IMA was measured spectrophotometrically using the albumin cobalt binding test.
Results: The serum IMA and corrected IMA levels were statistically significant between the groups, and the levels of IMA and corrected IMA were measured as SD patients group 0.70, 0.70 and control group 0.52, 0.51 ABSU (absorbance units), respectively (p

Key words: Seborrheic dermatitis, ischemia modified albumin, oxidative stress





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