Abstract

ABSTRACT
This study was conducted to evaluate the effect of Parsley (Petroselinum crispum) on some biochemical profiles in streptozotocin diabetic rats. For this purpose, 40 male albino rats were divided into 4 groups according to the program assigned 10 rats per group: Group 1: control group kept on basal ration, Group 2: Parsley group kept on basal ration + Parsley 2gm/kg body weight, Group 3: Diabetic group rats injected intra peritoneal with STZ 45mg/kg body weight and kept on basal diet, Group 4: Diabetic + Parsley rats injected intra peritoneal with STZ 45mg/kg body weight and kept on basal diet + Parsley 2gm/kg body weight. Results showed that: Treatment of the STZ induced diabetic rats with parsley resulted in significant decrease in fasting blood glucose and glycated haemoglobin compared to control group but there is no significant difference within all groups in fructose amine, Alanine aminotransferase, aspartate aminotransferase, Total protein, Albumin, Urea and Creatinine also in Total cholesterol, Triglyceride and HDL while STZ resulted in significant increase in liver antioxidants compared to Parsley treated group.

Key words: Diabetes mellitus, blood glucose, Streptozotocine, Parsley