There is a general agreement that vital pulp therapy in vital permanent teeth with cariously exposed pulps is a difficult process. A fast-setting calcium silicate-based cement material, Biodentine, has recently been in use in various clinical procedures as apexification, root perforations or resorptions, retrograde fillings, direct or indirect pulp capping procedures, and finally dentine replacement. Many of the recently published research articles recommended Biodentine as a vital pulp-capping material. Also, it is considered as a good dentine substitute. This review article explains different biochemical and vital pulp teeth clinical applications of this promising material.
Key words: Tricalcium silicate-based material, Biodentine, bioactivity, dentin substitute, material setting, clinical applications