The association between acromegaly and increased incidence of malignancy has been reported due to high GH and IGF levels. Although the incidence of all malignancies increases in patients with acromegaly, renal cell carcinoma (RCC) has been rarely reported. Herein, we report an acromegaly case with lung, gluteal and scapular metastatic RCC. The risk of cancer and cancer metastasis is high in uncontrolled acromegaly. At this point, treating acromegaly and controlling the disease progress are both important to enhance the life expectancy of a patient.
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