A total of 320 one-day-old Cobb chicks of mixed sex were used to investigate the impact of some amino acids supplementation and coccidial infection of broiler chicken on the growth performance, Immune response, some blood serum biochemical changes and intestinal morphology of broiler chickens. The chicks were randomly allotted into 10 equal groups, the first group were fed on the basal diet contain requirement of lysine (Ly), methionine (Met) and threonine (Thr) according to recommended catalog of the Cobb breed. Group 2 4 fed on the basal diet with 30% extra Ly, Met or Thr than recommended requirement respectively. Group 5 fed on the basal diet with extra combination of Ly, Met and Thr. Groups 6 10 fed on the same design as described for groups 1 5 with coccidial infection. It was found that the excess Ly, Met or Thr non-significantly increased the final body weight and significantly (P≤0.05) improved the feed efficiency and the performance index. Our data revealed that extra amino acids supplementation improved the blood picture and enhanced the immune response via increase the WBCs count and antibodies titer and significantly (P≤0.05) decreased blood serum carotenoids at 20th days of broiler age also reduced the coccidial fecal oocyst output at 14th or 28th days post-infection. It can be concluded that using of 30% extra methionine supplementation during the early age of broiler chickens and using 30% extra lysine supplementation during the grower and finisher period improved the performance and ameliorated the severity of coccidiosis.
Key words: Broiler chickens Growth performance Immune response Coccidial infection amino acids Ly- Met - Thr.
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