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Anaesth. pain intensive care. 2019; 23(1): 52-58


Outcome of pretreatment regimens on hemodynamic parameters and emergence during electroconvulsive therapy –A Study on Dexmedetomidine and Esmolol

Dixitkumar B Modh,Manthan P Parmar,Shilpin Solanki.




Abstract

Background and Aim: Electroconvulsive therapy (ECT) is a day care procedure commonly performed in indoor and outdoor patients of resistant psychiatric disorders. Present study was performed with an aim to observe the effect on hemodynamic parameters and emergence during electroconvulsive therapy using Dexmedetomidine and Esmolol as pretreatment regimen.
Material and methods: In our retrospective study, we had selected patients undergoing ECT from January 2017 to February 2018 in each group and described as follows- Group C: patients not received any pretreatment regimen. Group D: Inj. Dexmedetomidine 0.5 µg/kg diluted with 10 ml normal saline and administered over 10 minutes and Group E: Inj. Esmolol 1mg/kg diluted in 10 ml normal saline and administered over 2 minutes during preoxygenation. Pulse, systolic and diastolic blood pressure and SpO2 were measured at baseline value and compared after administration of drugs , 1 min, 3 min, 5min and 10 minutes after ECT shock and referred as “B”, “P”, “ E1, E3, E5, and E10” respectively. Recovery parameters and agitation score were assessed post ECT. Statistical analysis was performed by using SPSS package and P

Key words: Attenuation, Agitation, Dexmedetomidine, Electroconvulsive therapy, Esmolol






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