Influence of Volatile Organic Solvents Inhalation on Activity Quotient and Biochemical Indices of Mus musculus
Kenneth Victor Akpan, Temitope Olawunmi Sogbanmu, Adebayo Akeem Otitoloju.
Abstract
The influence of volatile organic solvents (nitrocellulose thinner, gasoline and xylene) on the activity quotient and liver biochemical indices of laboratory mice, Mus musculus over a period of 60 days were evaluated. The study entailed the use of a modified nose inhalation exposure method in which the exposure chambers were saturated with the test chemicals for 8 hours daily following which they were transferred to the vapour- free section of the chamber. The estimation of activity quotient by day 60 indicated that mice exposed to xylene were most restless followed by nitrocellulose thinner and gasoline (least restless) with activity quotient values of 0.69, 0.58 and 0.21 respectively. The results of the biochemical indices showed that there was a significant decrease (p
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