Hepatoprotective activity of methanolic shoot extract of Bambusa bambos against carbon tetrachloride induce acute liver toxicity in Wistar rats

J App Biol Biotech. 2018; 6(4): 37-40

doi: 10.7324/JABB.2018.60407

A. A. Shetti Suman Patil, H Joy Hoskeri, P Rajeev, Bhushan Kulkarni, Geetanjali R Kamble, Gurusiddhesh B Hiremath, Vishal Kalebar, S V Hiremath.

Abstract			Cited by 4 Articles
In the present study, Methanolic shoot extract of Bambusa bambus was analysed for its hepatoprotective activity against model hepatotoxicant CCl4 in Wistar rats by studying activity of AST, ALT, ALP and total bilirubin. The extract showed hepatoprotactive activity which was dose dependant and maximum beneficial effect was observed at a dose of 400 mg/kg. The results were comparable with that of standard drug, silymarin used in the study. The hepatoprotective action is perhaps related to its potent antioxidant activity. Further investigations are required to characterize the active hepatoprotective agent and mechanism of action. Key words: Bambusa bambus, Hepatoprotective, Methanolic extract, carbon tetrachloride (CCl4).