A total of 210 one-day-old dual purpose chicks of mixed sex were used to determine the activity of the chemical (based on organic acids salt) or biological (containing live yeast, yeast cell wall and some enzymes) commercial mycotoxin binder and minerals and to evaluate the protective effects of the binder on performance, carcass quality, some blood biochemical changes and immune status of broilers fed with Aflatoxin B1. The chicks were randomly allotted into 6 equal groups, the first group fed on the basal diet without any supplementation and considered as control, while groups 2 3 fed on the same basal diet with chemical and biological mycotoxin binder supplementation through drinking water respectively, while group 4 6 fed as mentioned for the first three groups with aflatoxin B1 (AFB1) contamination from 22th days of broiler age at a rate of 1mg of AFB1/Kg diet. It was found that aflatoxin feed contamination without mycotoxin binder supplementation significantly (P≤0.05) reduced the growth performance and deteriorated the feed efficiency parameters compared with broiler chicken group fed on the same diet without aflatoxin B1 contamination. On the other hand, chemical or biological mycotoxin binder supplementation with aflatoxin B1 contamination counteract the deleterious effect of aflatoxin B1 and significantly (P≤0.05) improved the growth performance compared with broiler chicken fed on the contaminated diet without mycotoxin binder supplementation. Our data indicated that mycotoxin binder supplementation significantly (P≤0.05) improved the immune response via increase the serum proteins level and improvement the WBCs level especially lymphocytes and neutrophils, phagocytic activity and index, antibodies production and immune organs weight of broiler chicken compared with control group fed on the basal diet without mycotoxin binder supplementation. It can be concluded that biological binder more immune stimulant in broiler chicken compared with chemical mycotoxin binder source.
Key words: Broiler chickens Growth performance Immune response Aflatoxin B1 Chemical and Biological Mycotoxin Binder.
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