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Original Research

RMJ. 2025; 50(4): 1060-1064


Development and Implementation of an Antimicrobial Stewardship Program in a Tertiary Care Hospital of Pakistan

Arslan Ahmer, Muhammad Ali Ghoto, Mah’d Musa Eid Abu Dhair, Rabia Mangi, Madiha Naz.



Abstract
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Objective: To design, implement, and evaluate the impact of a multidisciplinary Antimicrobial Stewardship Program (ASP) in a tertiary care hospital in rural Sindh.
Methodology: This prospective, quasi-experimental, interventional study was conducted from July 2023 to December 2024 at People’s Medical College Hospital, Nawabshah. It included 3000 adult inpatients (Using Cochran’s formula) receiving systemic antimicrobials. The intervention comprised audit and feedback, formulary restrictions, guideline development, and healthcare professional education. Key outcomes included antimicrobial consumption, prescription appropriateness, resistance trends, and clinical outcomes. Data were analyzed by SPSS v28, with p

Key words: Antimicrobial Stewardship Program, antimicrobial resistance, prescribing appropriateness, Pakistan.

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