Background: Secondary tumors in the breast from metastatic malignancies are rare. In the literature, an incidence of 1.3 to 2.7% is reported for breast metastases of extra-mammary origin. Melanoma malignum, pulmonary carcinoma, and Non-Hodgkin lymphoma are tumors that relatively more frequently spread to the breast. Ocular melanoma is an extremely rare form of cancer that affects the eye, with an incidence of 5 per million adults. The liver is the most common organ in the body affected by metastasis of an ocular melanoma (80% of cases), but less often may also involve the lungs, skin or soft tissue, and bone. Objective: The aim of this case report was to describe the a woman by presenting with choroid melanoma metastasizing to the breast, 4 years after enucleation of the eye. Case report: The management of metastasis and primary malignant breast tumors differs, which is why metastatic disease must be considered in any patient with a known history of primary malignant tumor who presents with a breast lump. A 37 year old women presented with a breast lump 4 years after enucleation of the eye for malignant melanoma of choroid, stage pT2b NxMx, followed by standard postoperative checkups. The patient underwent a mammography and ultrasonography. A CT scan of the abdomen showed metastatic disease. A core biopsy of the left breast lump showed a poorly differentiated malignancy, diffusely positive for MelanA, and S100. Conclusion: Metastatic disease from a choroid melanoma to the breast is a marker for disseminated metastatic spread with poor prognosis.
Key words: melanoma, choroid, metastasis, mammography, ultrasound, CORE biops
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