Background: Acute necrotizing encephalopathy is a neurological complication of influenza infection. ANE is characterized by periventricular white matter, brainstem, multifocal symmetric brain lesions in the thalamus and cerebellum. ANE is a rare and severe form of H1N1 encephalopathy.
Case presentation:
The presented case was of 11 years old boy who was diagnosed with acute necrotizing encephalopathy, the patient was clinically examined and several laboratory investigations, MRI as well as RT-PCR for H1N1 was done. The patient was found to be H1N1 positive and was treated with Oseltamivir, intravenous Igs and corticosteroids. The patient was discharged after 5 weeks.
Conclusion: Combination of Oseltamivir, corticosteroid and intravenous Igs are effective treatment for children having ANE and results in complete recovery.
Key words: acute, necrotizing encephalopathy, H1N1
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