Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation
Sana Sarfaraz, Rahila Najam.
Abstract
Objective: Beta vulgaris is an important part of daily diet and is consumed in salads. Current study was conducted to investigate the anti-inflammatory potential of lyophilized beet root powder.
Methodology: Albino rats weighing 140-200gm were chosen for this study. They were divided into six equal groups. For ethanoic acid induced paw edema model, group I was labeled as control and was orally given 1ml distilled water; groups II was given Ibuprofen as standard (400mg/70kg) and group III was given aqueous solution of lyophilized Beta vulgaris at dose of 500mg/kg. 30 minutes after giving these treatments 0.1 ml of 1% w/v ethanoic acid was administered in the subplantar tissue of rat paw. For carrrageenan induced paw edema method, group I (a), group II (a) and group III (a) were given same treatment as above divided groups; only difference was that they were administered 0.1ml of 1% carrageenan in subplantar tissue of rat paw after oral treatment. Swelling of paw was measured using Plethysmometer.
Results: Beta vulgaris had highly significant anti-inflammatory activity (p
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