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Anti-tumor effects of polyphenolic compounds of Camellia sinensis, Nigella sativa, Matricaria chamomilla and Triticum aesativum against Ehrlich ascites carcinoma mouse model

Mohamed Labib Salem, Abeer Abdel -Hamid Khamis, Abdel-Halim Abdel- Hady Mostafa, Ehab Mostafa Ali.




Abstract

1- Investigating the antioxidant and antitumor activities of combination of four selective medicinal plants
2- Effects of extracted polyphenolic compounds against Ehrlich ascites carcinoma cells in mice.
3- Evaluation of antitumor activities of polyphenolic extracts against Ehrlich ascites carcinoma cells in vitro.
4- Assessment the effect of polyphenolic compounds on apoptotic genes (Bad and Bax) and antiapoptotic genes (Bcl-2 and Bcl-xL) in Ehrlich ascites carcinoma cells.
5- Study the impact of cisplatin and polyphenolic compounds on level of total antioxidant capacity and activity of glutathione peroxidase.

Key words: Green tea, Chamomile, black cumin, Wheat bran, Glutathione peroxidase, Apoptosis.






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