| Original Article |
|  |
Novel associations of GSN indel and PLAG1 c.48333G > A variants with growth traits in mature Indonesian Madura and Bali cattleHartati Hartati, Widya Pintaka Bayu Putra, Mariyono Mariyono, Muhammad Luthfi, Lukman Affandhy, Dewi Khosiya Robba, Eko Handiwirawan, Sulistiyoningtiyas Irmawanti, Aryogi Aryogi, Susan Maphilindawati Noor, Endang Romjali, Wike Andre Septian. Abstract | Download PDF | | Post | Objectives: This study aimed to identify a 21 bp insertion/deletion mutation in the GSN gene (intron 2) and a single nucleotide polymorphism (c.48333G > A) in the PLAG1 gene (exon 3), and evaluate their association with growth traits in mature Madura and Bali cattle.
Materials and Methods: A total of 219 animals (156 Madura and 73 Bali cattle) were assessed for body weight (BW) and four body measurements: Heart girth (HG), body length (BL), hip height (HH), and withers height (WH). Genotyping was performed using PCR and PCR-RFLP techniques.
Results: Both genes were polymorphic, with high PIC values (> 0.30). The GSN gene polymorphism was significantly associated with HH in Bali cattle, while the PLAG1 gene showed significant associations with BW in both breeds.
Conclusions: These findings suggest that PLAG1 (c.48333G > A) is a promising genetic marker for BW in Indonesian tropical cattle.
Key words: Bali cattle, gene polymorphism, growth traits, GSN, Madura cattle, PLAG1
|
|
Bibliomed Article Statistics 18
 | R E A D S |  8
| D O W N L O A D S | | 05 | | | 2026 | |
|
|
|
|