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Microbial profile and antibiotic susceptibility pattern of orthopedic infections in a tertiary care hospital: A study from South India

Vasundhara Devi P, Sreenivasulu Reddy P, Shabnum M.




Abstract

Background: Orthopedic wound infections are one of the most important causes of morbidity and are difficult to treat. Changes in pathogenic microbial flora and the emergence of bacterial resistance are another problem in the management of orthopedic infections.

Objectives: In this regard, an attempt was made to know the bacteriological profile and their antibiotic susceptibility pattern in our hospital.

Materials and Methods: This study was conducted in the Department of Microbiology, Narayana Medical College & Hospital, Nellore, over a period of 1-year from June 2015 to May 2016. A total of 100 pus samples were collected and processed during the mentioned period.

Results: Out of the samples processed, 68 (68%) of specimens showed culture positivity. Pseudomonas aeruginosa 18 (26.4%) was the predominant isolate followed by Staphylococcus aureus 17 (25%). All Gram-positive cocci were susceptible to vancomycin and linezolid. Pseudomonas isolates were susceptible to polymyxin B, piperacillin-tazobactam, and meropenem.

Conclusion: Microbial analysis and their antibiogram of clinical samples are mandatory since it is deep seated infections with more pathogenic bacteria for optimal management of orthopedic infections.

Key words: Bacterial isolates; Antibiogram; Orthopedic infection; Wounds; Microbial flora






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