The recommended management of febrile neonates, in first 28 days of life is controversial. Given that the overall prevalence of serious bacterial infection is higher in the neonate, most experts would advocate for a full sepsis evaluation, and hospitalization for giving antibiotics. In recent years, opinions have been raised regarding the follow-up without hospitalization and antibiotics or follow-up even without hospitalization in febrile newborn infants. In our review the evidence for diagnostic accuracy of screening methods for identification of serious bacterial infection in febrile neonates will be evaluated.
Key words: Fever, serious bacterial infection, newborn, management
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