Abstract

Background
The resistance related with production of extended-spectrum beta-lactamase (ESBL) is an important problem that we face when we are treating infections caused by enterobacteriaceae. We aimed to evaluate the frequency of ESBL production in E. coli strains and the rate of antibiotic resistance isolated from in our microbiology laboratory.
Method
E. coli strains isolated from various clinical specimens between January 2010 – December 2011 were assessed retrospectively. Resistances to ESBL-producing and non-producing E. coli and the rate of ESBL production according to the years were investigated. The results were compared with statistical analysis.
Results
The rate of ESBL producing E. coli was 21.9% in 2010, and 25% in 2011. There was no resistance to imipenem, meropenem, ertapenem and tigecycline in all strains. The resistance to antibiotics other than amikacin was statistically significant in ESBL producing E. coli compared to ESBL non-producing E.coli (p

Key words: Antibiotic Resistance, Escherichia coli, ESBL

Article Language: Turkish English