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Original Article

J App Pharm Sci. 2016; 6(12): 124-130


Exposure of chitosan to UV/ozone: Structural information and antibacterial activity

Osiris W. Guirguis, Gehan T. El-Bassyouni, Mona A. Esawy, Nada R. Abd Elkader, Hadeer M. Mahmoud, Hend M. Mostafa, Nabawia A. Abdel-Zaher.




Abstract

In the present work, variation in the group coordination of chitosan due to the exposure to UV/ozone was considered by the FTIR reflectance. Pronounced variations in the intensities of reflectance bands and shifts in their positions were detected. This could be attributed to the change in the molecular configuration of chitosan. On the other hand, the well diffusion method was used to investigate the anti-bactericidal activities against two common bacterial strains [Bacillus subtitles (B. subtilis) and Escherichia coli (E. coli)] by detecting the mean inhibition zone diameters (IZD) against the microorganisms. The achieved data revealed that the chitosan exposed to UV/ozone confirmed a high potential of antibacterial activity.

Key words: Chitosan, Structural Information, FTIR, Antibacterial activity, UV/ozone treatment.






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