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Original Article

NOFOR. 2024; 3(3): 59-64


Biosafety at autopsy: Analysis of hepatitis B, hepatitis C, and HIV transmission risks

Mustafa Sen, Selcuk Cetin, Umut Safiye Say Coskun, Hasan Din, Sule Sinem Gedikbas.




Abstract

Aim: This study aimed to demonstrate, through serological testing, that healthcare workers involved in forensic autopsies are at risk for HIV, hepatitis B, and hepatitis C viruses, and to discuss the necessary precautions for infection control in light of the literature.
Materials and Methods: After completion of the forensic autopsy, two separate 5 ml blood samples were taken from the thigh regions of the corpses in gel tubes with yellow caps, with the written consent of the relatives of the deceased. The blood samples were analyzed for HBsAg, anti-HCV, and anti-HIV 1/2 levels using the Roche Cobas E601 device in the microbiology laboratory of the Research and Training Hospital of Gaziosmanpaşa University Faculty of Medicine, employing the electrochemiluminescence method.
Results: The study included 197 cases who underwent autopsy in Tokat and Kayseri provinces. The blood samples collected were analyzed for HBsAg, anti-HCV, and anti-HIV 1/2 levels. In the serological tests performed, HBsAg positivity was detected in 6 cases (3.04%) and anti-HCV positivity in 1 case (0.50%), while anti-HIV 1/2 positivity was not detected in any cases.
Conclusion: A risk assessment should always be carried out before the autopsy. Depending on the emerging risk and the biosafety level determined, protective measures should be taken. In cases where a risk assessment cannot be performed, biosafety principles should be strictly followed, and the bodies should be transferred to appropriate autopsy centers if necessary.

Key words: Autopsy, biosafety, infection, risk analysis.





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