Chemical investigation of the dichloromethane extracts of Hoya cagayanensis led to the isolation of dihydrocanaric acid (1), lupeol (2), lupenone (3) and saturated hydrocarbons from the stems; and 2-hydroxyethyl benzoate (4) and a mixture of β-sitosterol (5a) and stigmasterol (5b) from the leaves. The structures of 1 and 4 were elucidated by extensive 1D and 2D NMR spectroscopy. The structures of 2, 3, 5a and 5b were identified by comparison of their NMR data with literature data.
Key words: Apocynaceae, dihydrocanaric acid, Hoya cagayanensis C. M. Burton, 2-hydroxyethyl benzoate, lupenone, lupeol, saturated hydrocarbons, β-sitosterol, stigmasterol
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