Caudal regression syndrome (CRS) is a spectrum of disorders of caudal vertebral agenesis or dysgenesis, involving the caudal spinal column, that is associated with other congenital anomalies.
The majority of caudal regression cases are sporadic but maternal pre-gestational diabetes is the main risk factor.
Imaging is an integral part of management of caudal regression syndrome. Antenatal diagnosis on obstetric ultrasound and evaluation with fetal MRI is ideal. Early postnatal diagnosis and/or detailed evaluation with MRI is essential for early management to improve outcomes.
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